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Clinical relevance of circulating angiogenic factors in patients with non-Hodgkin’s lymphoma or Hodgkin’s lymphoma by Francis J Giles; Julie M Vose; Kim-Anh Do; Marcella M Johnson; Taghi Manshouri; Gregory Bociek; Philip J Bierman; Susan M O’Brien; Hagop M Kantarjian; James O Armitage; Maher Albitar is a Medicine article available to read on EtoBox.

What is Clinical relevance of circulating angiogenic factors in patients with non-Hodgkin’s lymphoma or Hodgkin’s lymphoma about?

Vascular endothelial growth factor (VEGF), basic-fibroblast growth factor (bFGF), hepatocyte growth factor (HGF), and angiogenin are important angiogenic factors. In 65 patients with non-Hodgkin's lymphoma (NHL), pre-treatment VEGF, bFGF, and HGF levels were significantly elevated compared to normal individuals, while angiogenin levels were significantly subnormal. In 37 patients with Hodgkin's disease, pre-treatment levels of VEGF and HGF were significantly elevated, bFGF levels were normal, and angiogenin levels were significantly subnormal. In patients with NHL, post-therapy levels of angiogenin were independently predictive of survival. Both pre-therapy and post-therapy VEGF levels were independently predictive of survival in patients with HD.

Who reads Clinical relevance of circulating angiogenic factors in patients with non-Hodgkin’s lymphoma or Hodgkin’s lymphoma?

Author

Francis J Giles; Julie M Vose; Kim-Anh Do; Marcella M Johnson; Taghi Manshouri; Gregory Bociek; Philip J Bierman; Susan M O’Brien; Hagop M Kantarjian; James O Armitage; Maher Albitar

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0145-2126)

Published

2004

Language

EN

Field

Medicine (Health Sciences)