Can I read Targeted Therapies in Breast Cancer (Oxford American Pocket Notes) on EtoBox?

Targeted Therapies in Breast Cancer (Oxford American Pocket Notes) by Harold J. Burstein is a book available to read on EtoBox.

What is Targeted Therapies in Breast Cancer (Oxford American Pocket Notes) about?

The development of monoclonal antibodies and other inhibitors of specific molecules, fully utilizing the insights learned from molecular techniques such as comparative microarrays and protein expression patterns, has led to the development and FDA approval of several agents for the treatment of breast cancer, such as trastuzamab (Herceptin, targeting HER-2 positive tumors) and lapatinib (Tykerb, targeting tumors with mutated/overexpressed EGFR 1 and 2). Other agents specifically targeting the estrogen receptor, the aromatose pathway and microtubule dynamics, fulvestrant (Faslodex, targeting the ER specifically in breast cancer cells), and letrozole (Femara, targeting the aromatose pathway), raloxifene (Evista, a selective estrogen receptor modulator), ixabepilone (Ixempra, a?-tubulin inhibitor) have also been approved for various stages and specific settings in breast cancer treatment. The current challenges in the field include further targeting of these agents as part of specific strategies for each patient (biomarker testing, pharmacogenetics, etc.), as well as follow-up and management of adverse events. Part of the Oxford American Pocket Notes series, this volume provides clini

Author

Harold J. Burstein

Publisher

Oxford ; New York: Oxford University Press

Published

2011

Language

EN

ISBN

9780199735679

Subjects

Medical, Medicine