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Multiple biopsies of normal-looking urothelium in patients with superficial bladder cancer: Are they necessary? by NAOHIRO FUJIMOTO; SHUJI HARADA; MICHIKAZU TERADO; HIDEKI SATO; TETSURO MATSUMOTO is a Medicine article available to read on EtoBox.

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## Abstract **Background:** The objective of the study presented here was to assess the usefulness and indications of multiple biopsies of normal‐appearing urothelium in patients with superficial bladder cancer. **Methods:** Between December 1996 and December 2002, multiple biopsies of normal‐appearing bladder mucosa were performed in 100 patients with superficial bladder transitional cell carcinoma. Biopsy specimens were taken from seven different sites in females and nine different sites in males. **Results:** In eight of 100 patients, bladder cancers were detected in the biopsy specimens. Three cases were Ta and five were Tis. All of the five patients with carcinoma __in situ__ (CIS) in their biopsy specimens had multiple papillary broad‐base tumors and positive urinary cytology. The detection ratio of CIS in patients with these findings was 17.9% (5/28). No concomitant CIS was detected in the 72 patients who had a solitary tumor, pedunculated tumor(s), or negative urinary cytology. **Conclusion:** Multiple mucosal biopsies of normal‐appearing urothelium are not necessary for all patients with superficial bladder cancer. They are, however, necessary for patients with multiple pa

Who reads Multiple biopsies of normal-looking urothelium in patients with superficial bladder cancer: Are they necessary??

Author

NAOHIRO FUJIMOTO; SHUJI HARADA; MICHIKAZU TERADO; HIDEKI SATO; TETSURO MATSUMOTO

Publisher

John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley (ISSN 0919-8172)

Published

2003

Language

EN

Field

Medicine (Health Sciences)