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Cardiac magnetic resonance derived global longitudinal strain outperfoms established functional parameters in prognostication after ST-elevation myocardial infarction by M Holzknecht; M Reindl; C Tiller; I Lechner; T Hornung; D Plappert; G Klug; S.J Reinstadler; A Bauer; A Mayr; B Metzler is a Medicine article available to read on EtoBox.
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## Abstract ## Background Left ventricular ejection fraction (LVEF) is the parameter of choice for left ventricular (LV) function assessment and risk stratification of patients with ST-elevation myocardial infarction (STEMI); however, its prognostic value is limited. Other measures of LV function such as global longitudinal strain (GLS) and mitral annular plane systolic excursion (MAPSE) might provide additional prognostic information post-STEMI. However, comprehensive investigations comparing these parameters in terms of prediction of hard clinical events following STEMI are lacking so far. ## Purpose We aimed to investigate the comparative prognostic value of LVEF, MAPSE and GLS by cardiac magnetic resonance (CMR) imaging in the acute stage post-STEMI for the occurrence of major adverse cardiac events (MACE). ## Methods This observational study included 407 consecutive acute STEMI patients treated with primary percutaneous coronary intervention (PCI). Comprehensive CMR investigations were performed 3 [interquartile range (IQR): 2–4] days after PCI to determine LVEF, GLS and MAPSE as well as myocardial infarct characteristics. Primary endpoint was the occurrence of MACE defined as
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- Author
- M Holzknecht; M Reindl; C Tiller; I Lechner; T Hornung; D Plappert; G Klug; S.J Reinstadler; A Bauer; A Mayr; B Metzler
- Publisher
- Oxford University Press (OUP)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)