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This study investigates the use of chitosan nerve grafts incorporated with extracellular vesicles (EVs) from skin-derived precursor Schwann cells (SKP-SC-EVs) to enhance peripheral nerve regeneration in a rat model. Results show that the incorporation of SKP-SC-EVs significantly improves motor and sensory function recovery, axonal outgrowth, and myelination compared to conventional nerve conduits. The findings suggest that SKP-SC-EVs represent a promising strategy for repairing long-distance peripheral nerv

Author

gabrieldeclercq0

Language

EN