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Can I read OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers on EtoBox?
OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers by N. Pandya; W. Chen; J. Lohr; X.-T. Yao; R. Burns; H. Li; H. Li; J. Muth; R. Goldwater; E. Bonvini; S. Johnson; P. Moore; J. Wigginton is a Medicine article available to read on EtoBox.
What is OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers about?
and success) of individual funding requests for treatments apparently varied between interviewees. Often advances in the clinical evidence were used to justify deviations from guidelines. However the influence of evidence had a lesser role in dose-optimisation decisions in remission, where the evidence to guide such decisions is limited. Conclusions: The results suggest that a range of factors, other than just cost, may influence anti-TNF prescribing decisions including the emergence of evidence, the interpretation of clinical guidelines, patient involvement in decision making, a desire for clinical autonomy and the influence of clinical service commissioners. Such factors generate variability in the treatment received by patients with rheumatoid arthritis across England. Further research could explore whether the variation in deviations from NICE guidance leads to differences in patient outcomes or the cost-effectiveness of care. References: [1] a: NICE (2016). Technology Appraisal 375.
Who reads OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers?
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- Author
- N. Pandya; W. Chen; J. Lohr; X.-T. Yao; R. Burns; H. Li; H. Li; J. Muth; R. Goldwater; E. Bonvini; S. Johnson; P. Moore; J. Wigginton
- Publisher
- BMJ
- Published
- 2016
- Language
- EN
- Field
- Medicine (Health Sciences)