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Effectiveness of Radiotherapy for Elderly Patients With Glioblastoma by Jacob Scott; Ya-Yu Tsai; Prakash Chinnaiyan; Hsiang-Hsuan Michael Yu is a Medicine article available to read on EtoBox.

What is Effectiveness of Radiotherapy for Elderly Patients With Glioblastoma about?

Purpose: Radiotherapy plays a central role in the definitive treatment of glioblastoma. However, the optimal management of elderly patients with glioblastoma remains controversial, as the relative benefit in this patient population is unclear. To better understand the role that radiation plays in the treatment of glioblastoma in the elderly, we analyzed factors influencing patient survival using a large population-based registry. Methods and Materials: A total of 2,836 patients more than 70 years of age diagnosed with glioblastoma between 1993 and 2005 were identified from the Surveillance, Epidemiology, and End Results (SEER) registry. Demographic and clinical variables used in the analysis included gender, ethnicity, tumor size, age at diagnosis, surgery, and radiotherapy. Cancer-specific survival and overall survival were evaluated using the Kaplan-Meier method. Univariate and multivariate analysis were performed using Cox regression. Results: Radiotherapy was administered in 64% of these patients, and surgery was performed in 68%. Among 2,836 patients, 46% received surgery and radiotherapy, 22% underwent surgery only, 18% underwent radiotherapy only, and 14% did not undergo eit

Who reads Effectiveness of Radiotherapy for Elderly Patients With Glioblastoma?

Author

Jacob Scott; Ya-Yu Tsai; Prakash Chinnaiyan; Hsiang-Hsuan Michael Yu

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2011

Language

EN

Field

Medicine (Health Sciences)