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What is Evaluating Avicel PH 105 Granules with Binders about?
1. The study characterized and evaluated changes in granule properties of Avicel PH 105 using two grades of Methocel binders, K100M CR and K4M CR, through rheological and thermal analysis techniques. 2. The end point of wet granulation was determined to be 55% w/w of binder solution for both grades. 3. Testing showed granules prepared with Methocel K100M CR had better flowability, permeability and compressibility than those prepared with Methocel K4M CR based on rheological measurements.
- Author
- Him
- Language
- EN