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Increasing levels of Parasutterella in the gut microbiome correlate with improving low-density lipoprotein levels in healthy adults consuming resistant potato starch during a randomised trial by Bush, Jason R.; Alfa, Michelle J. is a Medicine article available to read on EtoBox.

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## Abstract ## Background Prebiotics, defined as a substrate that is selectively utilized by host microorganisms conferring a health benefit, present a potential option to optimize gut microbiome health. Elucidating the relationship between specific intestinal bacteria, prebiotic intake, and the health of the host remains a primary microbiome research goal. ## Objective To assess the correlations between gut microbiota, serum health parameters, and prebiotic consumption in healthy adults. ## Methods We performed ad hoc exploratory analysis of changes in abundance of genera in the gut microbiome of 75 participants from a randomized, placebo-controlled clinical trial that evaluated the effects of resistant potato starch (RPS; MSPrebiotic®, N = 38) intervention versus a fully digestible placebo (N = 37) for which primary and secondary outcomes have previously been published. Pearson correlation analysis was used to identify relationships between health parameters (ie. blood glucose and lipids) and populations of gut bacteria. ## Results Abundance of Parasutterella (phylum Proteobacteria) tended to increase in the gut microbiome of individuals consuming RPS and those increases in Paras

Who reads Increasing levels of Parasutterella in the gut microbiome correlate with improving low-density lipoprotein levels in healthy adults consuming resistant potato starch during a randomised trial?

Author

Bush, Jason R.; Alfa, Michelle J.

Publisher

Springer (Biomed Central Ltd.); London: BioMed Central, [2015]-; Springer Science and Business Media LLC (ISSN 2055-0928)

Published

2020

Language

EN

Field

Medicine (Health Sciences)