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Can I read Cardiovascular Adaptation to Orthostatic Stress During Vasodilator Therapy* on EtoBox?
Cardiovascular Adaptation to Orthostatic Stress During Vasodilator Therapy* by Lipsitz, Lewis A.; Connelly, Carolyn M.; Kelley-Gagnon, Margaret; Kiely, Dan K.; Abernethy, Darrell; Waksmonski, Carol is a Medicine article available to read on EtoBox.
What is Cardiovascular Adaptation to Orthostatic Stress During Vasodilator Therapy* about?
## Background: Orthostatic hypotension is a dangerous problem in elderly patients, often exacerbated by vasodilator medications. age- and disease-related impairments in cardioacceleration and diastolic ventricular function may make older patients particularly vulnerable to the hypotensive effects of these drugs. therefore we aimed to determine mechanisms of postural blood pressure regulation in elderly patients with coronary artery disease and to compare the effects of isosorbide dinitrate and nicardipine hydrochloride on postural blood pressure homeostasis in these patients. ## Methods: Twenty elderly subjects with stable coronary artery disease (age, 76 +/- 4 [sd] years) underwent a baseline evaluation followed by a double-blind, randomized crossover comparison of nicardipine (20 mg by mouth t.i.d.) versus isosorbide (20 mg by mouth t.i.d.). doppler echocardiography and a 15-minute 60-degree head-up tilt test were conducted on no study medications and then after successive 3-week treatment periods with nicardipine or isosorbide. blood pressure, heart rate, vascular resistance, cardiac output, and spectral characteristics of heart rate and blood pressure variability were measured
Who reads Cardiovascular Adaptation to Orthostatic Stress During Vasodilator Therapy*?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Lipsitz, Lewis A.; Connelly, Carolyn M.; Kelley-Gagnon, Margaret; Kiely, Dan K.; Abernethy, Darrell; Waksmonski, Carol
- Publisher
- Nature Publishing Group; Wiley (Blackwell Publishing); Wiley-Blackwell; Wiley; Springer Science and Business Media LLC; Research Square (ISSN 0009-9236)
- Published
- 1996
- Language
- EN
- Field
- Medicine (Health Sciences)