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Strub 2010 by pablozglez is a document available to read on EtoBox.
The study investigates the role of sphingosine-1-phosphate (S1P) produced by sphingosine kinase 2 (SphK2) in mitochondria, highlighting its interaction with prohibitin 2 (PHB2) to regulate the assembly of cytochrome-c oxidase (complex IV) and mitochondrial respiration. The findings indicate that S1P binds specifically to PHB2, and its absence leads to impaired mitochondrial function and respiration. This research suggests a novel intracellular role for S1P beyond its known signaling through G-protein-couple
- Author
- pablozglez
- Language
- EN