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Can I read Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis on EtoBox?
Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis by Tao Guo; Anton E.P. Adang; Guizhen Dong; Dan Fitzpatrick; Peng Geng; Koc-Kan Ho; Charles H. Jibilian; Steven G. Kultgen; Ruiyan Liu; Edward McDonald; Kurt W. Saionz; Kenneth J. Valenzano; Nicole C.R. van Straten; Dan Xie; Maria L. Webb is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis about?
Potent small molecule biaryl diketopiperazine FSH receptor agonists such as 10c (EC 50 =13 nM) and 11f (EC 50 =1.2 nM) were discovered through the design, synthesis and evaluation of three biaryl diketopiperazine optimization libraries with over 300 compounds. These libraries were prepared via solid-phase parallel synthesis using a cyclization-release method.
Who reads Small molecule biaryl FSH receptor agonists. Part 2: Lead optimization via parallel synthesis?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Tao Guo; Anton E.P. Adang; Guizhen Dong; Dan Fitzpatrick; Peng Geng; Koc-Kan Ho; Charles H. Jibilian; Steven G. Kultgen; Ruiyan Liu; Edward McDonald; Kurt W. Saionz; Kenneth J. Valenzano; Nicole C.R. van Straten; Dan Xie; Maria L. Webb
- Publisher
- Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0960-894X)
- Published
- 2004
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)