About this document
Efficient Protein Production via Circular mRNA by Saptak Saha is a document available to read on EtoBox.
The article presents two molecular designs that enhance the translation efficiency of circular mRNA through an internal cap-initiated mechanism. The first design involves a covalently attached m7G cap, while the second utilizes a non-covalent attachment via hybridization, both significantly improving protein production compared to traditional methods. These advancements aim to broaden the therapeutic applications of circular mRNAs by increasing translation efficiency and reducing immune responses.
- Author
- Saptak Saha
- Language
- EN