Can I read The Genetics of Spondyloarthropathies on EtoBox?

The Genetics of Spondyloarthropathies by Maxime Breban; Corinne Miceli-Richard; Elena Zinovieva; Dominique Monnet; Roula Said-Nahal is a Medicine article available to read on EtoBox.

What is The Genetics of Spondyloarthropathies about?

The spondyloarthropathies constitute a group of inflammatory joint diseases linked by shared characteristics that include a strong common genetic background. Genetic factors include major histocompatibility complex (MHC) genes, among which HLA-B27 contributes 30% of the overall genetic susceptibility to spondyloarthropathies, and non-MHC genes, none of which have been identified to date. Genome screens have identified regions that may contain susceptibility genes for spondyloarthropathies. In particular, a locus on the long arm of chromosome 9 (9q31-34) was identified by two groups working independently from each other. Studies using the candidate gene approach ruled out a role for most of the tested genes, including CARD15/NOD2. However, several independent groups have reported significant associations between ankylosing spondylitis and the IL-1 gene cluster on the long arm of chromosome 2.

Who reads The Genetics of Spondyloarthropathies?

Author

Maxime Breban; Corinne Miceli-Richard; Elena Zinovieva; Dominique Monnet; Roula Said-Nahal

Publisher

Elsevier BV

Published

2006

Language

EN

Field

Medicine (Health Sciences)