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Patterns of Failure after Intensity Modulated Radiation Therapy (IMRT) for Nasopharyngeal Cancer by S.S. Arif; A.J. Bayley; B. O'Sullivan; B.J. Cummings; S. Fung; E. Yu; S.L. Breen; E. Chen; J.N. Waldron; J.J. Kim is a Medicine article available to read on EtoBox.
What is Patterns of Failure after Intensity Modulated Radiation Therapy (IMRT) for Nasopharyngeal Cancer about?
Purpose/Objective(s): Compared to CRT, IMRT improves quality of life and salivary function for patients with HNC undergoing radiotherapy, but no randomized trial has shown a difference in OS. We used the NCI Surveillance, Epidemiology and End Results -Medicare linked database (SEER-Medicare) from 2002-2005 to analyze survival for patients over the age of 65 who received IMRT or CRT for HNC. Materials/Methods: OS, cancer specific survival (CSS), and non-cancer specific survival (NCSS) were assessed among 2,231 HNC patients with localized cancer of the oral cavity, nasal cavity, nasopharynx, hypopharynx, oropharynx, and salivary glands. Lip and larynx were excluded due to low rates of IMRT use (5.13% and 13.95%). Covariates included Elixhauser comorbidity score, age, race, sex, anatomic site, presence of positive lymph nodes, localized vs. regional disease, urban vs. rural residence, and income quartile by census tract, and were tested using multivariable Cox proportional hazards analysis. We analyzed the entire cohort as well as 4 subgroups of patients based on type of radiation received (primary versus postoperative) and use of concurrent chemotherapy (CT): Prim RT (N = 549), Prim
Who reads Patterns of Failure after Intensity Modulated Radiation Therapy (IMRT) for Nasopharyngeal Cancer?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- S.S. Arif; A.J. Bayley; B. O'Sullivan; B.J. Cummings; S. Fung; E. Yu; S.L. Breen; E. Chen; J.N. Waldron; J.J. Kim
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)