Can I read Latent Class Analysis with Semi-parametric Proportional Hazards Submodel for Time-to-event Data on EtoBox?

Latent Class Analysis with Semi-parametric Proportional Hazards Submodel for Time-to-event Data by Fei, Teng; Hanfelt, John; Peng, Limin is a scholarly article available to read on EtoBox.

What is Latent Class Analysis with Semi-parametric Proportional Hazards Submodel for Time-to-event Data about?

Latent class analysis (LCA) is a useful tool to investigate the heterogeneity of a disease population with time-to-event data. We propose a new method based on non-parametric maximum likelihood estimator (NPMLE), which facilitates theoretically validated inference procedure for covariate effects and cumulative hazard functions. We assess the proposed method via extensive simulation studies and demonstrate improved predictive performance over standard Cox regression model. We further illustrate the practical utility of the proposed method through an application to a mild cognitive impairment (MCI) cohort dataset.

Author

Fei, Teng; Hanfelt, John; Peng, Limin

Published

2022

Language

EN