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Enthesitis in Psoriatic Arthritis (Part 1) - Pathophysiology2020 by Diana GC is a document available to read on EtoBox.

What is Enthesitis in Psoriatic Arthritis (Part 1) - Pathophysiology2020 about?

The document discusses the pathophysiology of enthesitis in psoriatic arthritis (PsA). It describes entheses as structures that connect tendons and ligaments to bone, and how they are involved in mechanical force transduction and stability. Exaggerated inflammatory responses to mechanical stress in PsA patients leads to enthesitis initiation. Key mediators include IL-17, IL-23, TNF-α, and PGE2, which activate innate immune cells and drive chronic inflammation and new bone formation.

Author

Diana GC

Language

EN