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A Long Duration of Intraoperative Hypotension Is Associated with Postoperative Delirium Occurrence Following Thoracic and Orthopedic Surgery in Elderly by Wen Duan; Cheng-Mao Zhou; Jin-Jin Yang; Yue Zhang; Ze-Ping Li; Da-Qing Ma; Jian-Jun Yang is a Medicine article available to read on EtoBox.
What is A Long Duration of Intraoperative Hypotension Is Associated with Postoperative Delirium Occurrence Following Thoracic and Orthopedic Surgery in Elderly about?
Background Postoperative delirium (POD) is a common surgical complication associated with increased morbidity and mortality in elderly. Although the underlying mechanisms remain elusive, perioperative risk factors were reported to be closely related to its development. This study was designed to investigate the association between the duration of intraoperative hypotension and POD incidence following thoracic and orthopedic surgery in elderly. Method The perioperative data from 605 elderly undergoing thoracic and orthopedic surgery from January 2021 to July 2022 were analyzed. The primary exposure was a cumulative duration of mean arterial pressure (MAP) ≤ 65 mmHg. The primary end-point was the POD incidence assessed with confusion assessment method (CAM) or CAM-ICU for three days after surgery. Restricted cubic spline (RCS) was conducted to examine the continuous relationship between the duration of intraoperative hypotension and POD incidence adjusted with patients' demographics and surgery related factors. Then the duration of intraoperative hypotension was categorized into three groups: no hypotension, short (< 5 mins) or long duration (≥ 5 mins) of hypotension for further anal
Who reads A Long Duration of Intraoperative Hypotension Is Associated with Postoperative Delirium Occurrence Following Thoracic and Orthopedic Surgery in Elderly?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Wen Duan; Cheng-Mao Zhou; Jin-Jin Yang; Yue Zhang; Ze-Ping Li; Da-Qing Ma; Jian-Jun Yang
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Health Sciences)