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Can I read Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation: A Comparative Modeling Study on EtoBox?
Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation: A Comparative Modeling Study by Jennifer M. Yeh; Kathryn P. Lowry; Clyde B. Schechter; Lisa R. Diller; Oguzhan Alagoz; Gregory T. Armstrong; John M. Hampton; Wendy Leisenring; Qi Liu; Jeanne S. Mandelblatt; Diana L. Miglioretti; Chaya S. Moskowitz; Kevin C. Oeffinger; Amy Trentham-Dietz; Natasha K. Stout is a Medicine article available to read on EtoBox.
What is Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation: A Comparative Modeling Study about?
## Background: Surveillance with annual mammography and breast magnetic resonance imaging (mri) is recommended for female survivors of childhood cancer treated with chest radiation, yet benefits, harms, and costs are uncertain. ## Objective: To compare the benefits, harms, and cost-effectiveness of breast cancer screening strategies in childhood cancer survivors. ## Design: Collaborative simulation modeling using 2 cancer intervention and surveillance modeling network breast cancer models. ## Data sources: Childhood cancer survivor study and published data. ## Target population: Women aged 20 years with a history of chest radiotherapy. ## Time horizon: Lifetime. ## Perspective: Payer. ## Intervention: Annual mri with or without mammography, starting at age 25, 30, or 35 years. ## Outcome measures: Breast cancer deaths averted, false-positive screening results, benign biopsy results, and incremental cost-effectiveness ratios (icers). ## Results of base-case analysis: Lifetime breast cancer mortality risk without screening was 10% to 11% across models. compared with no screening, starting at age 25 years, annual mammography with mri averted the most deaths (56% to 71%) and annual mri
Who reads Clinical Benefits, Harms, and Cost-Effectiveness of Breast Cancer Screening for Survivors of Childhood Cancer Treated With Chest Radiation: A Comparative Modeling Study?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Jennifer M. Yeh; Kathryn P. Lowry; Clyde B. Schechter; Lisa R. Diller; Oguzhan Alagoz; Gregory T. Armstrong; John M. Hampton; Wendy Leisenring; Qi Liu; Jeanne S. Mandelblatt; Diana L. Miglioretti; Chaya S. Moskowitz; Kevin C. Oeffinger; Amy Trentham-Dietz; Natasha K. Stout
- Publisher
- American College of Physicians (ISSN 0003-4819)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)