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The development in rating-based executive functions in children at familial high risk of schizophrenia or bipolar disorder from age 7 to age 11: the Danish high risk and resilience study by Anna Krogh Andreassen; Rikke Lambek; Aja Greve; Nicoline Hemager; Christina Bruun Knudsen; Lotte Veddum; Merete Birk; Anne Søndergaard; Julie Marie Brandt; Maja Gregersen; Mette Falkenberg-Krantz; Katrine Søborg Spang; Jessica Ohland; Birgitte Klee Burton; Jens Richardt Møllegaard Jepsen; Anne Amalie Elgaard Thorup; Merete Nordentoft; Ole Mors; Vibeke Fuglsang Bliksted is a Psychology article available to read on EtoBox.

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Executive functions (EF) deficits are well documented in children at familial high risk of schizophrenia (FHR-SZ), and to a lesser degree in children at familial high risk of bipolar disorder (FHR-BP). The aim of this study was to assess EF development in preadolescent children at FHR-SZ, FHR-BP and population-based controls (PBC) using a multi-informant rating scale. A total of 519 children (FHR-SZ, n = 201; FHR-BP, n = 119; PBC, n = 199) participated at age 7, at age 11 or at both time points. Caregivers and teachers completed the Behavior Rating Inventory of Executive Functions (BRIEF). The developmental pattern from age 7 to age 11, did not differ between groups. At age 11, caregivers and teachers rated children at FHR-SZ as having widespread EF deficits. A higher proportion of children at FHR-SZ had clinically significant scores on the General executive composite (GEC) and all BRIEF indices compared to PBC. According to the caregivers, children at FHR-BP had significantly more EF deficits than PBC on 9 out of 13 BRIEF scales, whereas according to teachers, they only had significantly more deficits on one subdomain (Initiate). Likewise, caregivers rated a significantly higher p

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Author

Anna Krogh Andreassen; Rikke Lambek; Aja Greve; Nicoline Hemager; Christina Bruun Knudsen; Lotte Veddum; Merete Birk; Anne Søndergaard; Julie Marie Brandt; Maja Gregersen; Mette Falkenberg-Krantz; Katrine Søborg Spang; Jessica Ohland; Birgitte Klee Burton; Jens Richardt Møllegaard Jepsen; Anne Amalie Elgaard Thorup; Merete Nordentoft; Ole Mors; Vibeke Fuglsang Bliksted

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Psychology (Social Sciences)