Can I read Detection rates of a national fetal anomaly screening programme: A national cohort study on EtoBox?

Detection rates of a national fetal anomaly screening programme: A national cohort study by Nicholas Aldridge; Pranav Pandya; Judith Rankin; Nicola Miller; Jennifer Broughan; Nadia Permalloo; Annette McHugh; Sarah Stevens is a Medicine article available to read on EtoBox.

What is Detection rates of a national fetal anomaly screening programme: A national cohort study about?

## Objective: To measure condition-specific detection rates for 14 physical conditions screened for by the nhs fetal anomaly screening programme (fasp) fetal anomaly (fa) ultrasound scan. ## Design: Retrospective audit of 12 694 diagnoses across a 3-year national cohort. ## Setting: All english nhs and crown-dependency hospital trusts providing maternity services. ## Population: Pregnancies booked for maternity services with an expected date of delivery between 1 april 2017 and 31 march 2020 and at least one diagnosis of a condition screened for by fasp. ## Methods: Active multi-source ascertainment, linkage, audit and validation of clinical information to identify the subset of diagnoses meeting the condition-specific positivity threshold for the fa scan. ## Main outcome measure: The accuracy of the fa scan compared with diagnostic reference standards. ## Results: Fa scan detection rates were: anencephaly 96.3% (95% confidence interval [ci] 81.7-99.3%), atrioventricular septal defect: 69.2% (95% ci 65.8-72.4%), bilateral renal agenesis: 98.7% (95% ci 95.4-99.6%), cleft lip: 89.5% (95% ci 87.8-90.9%), congenital diaphragmatic hernia: 60.8% (95% ci 56.5-65%), edwards syndrome: 73.8%

Who reads Detection rates of a national fetal anomaly screening programme: A national cohort study?

Author

Nicholas Aldridge; Pranav Pandya; Judith Rankin; Nicola Miller; Jennifer Broughan; Nadia Permalloo; Annette McHugh; Sarah Stevens

Publisher

Wiley

Published

2022

Language

EN

Field

Medicine (Health Sciences)