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This study investigates the anti-inflammatory effects of a triterpenoid compound, (21α)-22-hydroxyhopan-3-one, isolated from the medicinal plant Balanophora laxiflora, traditionally used in Vietnam. The compound demonstrated significant inhibition of COX-2 expression and reduced inflammatory mediators in macrophages, as well as alleviating inflammation in animal models. The mechanism of action involves decreasing reactive oxygen species levels and inhibiting MAPK signaling pathways, suggesting its potential

Author

thuyduongcp

Language

EN