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Reply by Renata Rogacka; Alaide Chieffo; Antonio Colombo is a Medicine article available to read on EtoBox.

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We read with great interest the article by Rogacka et al. (1). We applaud the authors' attempt to clarify the time course for hemorrhagic risk to these patients. Rogacka et al. (1) showed that most hemorrhagic events in patients on triple therapy (TT) (dual antiplatelet [DAP] plus oral anticoagulation [AC]) occurred within the first month of treatment and that half of these patients died. These hemorrhagic complications are common, real-world issues that impact the type of stents physicians select. Therefore, proper interpretation of these data (to aid decision making in everyday practice) is crucial. Unfortunately, the authors did not address the risk of recurrent bleeding during the 21-month follow-up period in patients who suffered a major bleeding event in the first month of TT. For example, in patients with nonvariceal upper gastrointestinal bleeds, rebleeding can be as high as 20% (2). It is unclear whether this study censored patients after the first bleeding event or if their TT was altered. Because current American College of Cardiology/American Heart Association recommendations now call for a minimum of 12 months DAP therapy after drug-eluting stent (DES) implantation, if

Who reads Reply?

Author

Renata Rogacka; Alaide Chieffo; Antonio Colombo

Publisher

American College of Cardiology; Elsevier ; Elsevier BV (ISSN 1936-8798)

Published

2008

Language

EN

Field

Medicine (Health Sciences)