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What is Improved Adapalene Preparation Process about?

This patent application describes an improved process for preparing adapalene, which is used to treat acne. The process aims to produce high purity adapalene more efficiently and economically than prior methods. It involves three steps: 1) preparing the adapalene methyl ester intermediate, 2) hydrolyzing this to adapalene, and 3) converting adapalene to the potassium salt form. The application also provides a method for quantitatively measuring color impurities in adapalene that may affect its appearance.

Author

Con Bò Sữa Thất Tình

Language

EN