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Can I read Tumor necrosis factor α (TNF-α) activates human adenoidal and cutaneous mast cells to histamine secretion on EtoBox?
Tumor necrosis factor α (TNF-α) activates human adenoidal and cutaneous mast cells to histamine secretion by Ewa Brzezińska-Błaszczyk; Anna Pietrzak is a Immunology and Microbiology article available to read on EtoBox.
What is Tumor necrosis factor α (TNF-α) activates human adenoidal and cutaneous mast cells to histamine secretion about?
It is widely known that mast cells and cytokine TNF-GI are both involved in inflammatdry reactions. Therefore, we have studied whether TNF-a can cause histamine secretion from human adenoidal and cutaneous mast cells. The experiments were performed in vitro on mast cells isolated from tissues by enzymatic dispersion technique. The results of our experiments have clearly shown that this cytokine stimulates mast cells to histamine release. TNF-cc-induced histamine release was concentration-and time-dependent. Moreover, the release of histamine evoked by TNF-c( was also dependent on reaction temperature and on glycolytic and oxidative cellular metabolism. We have concluded that TNF-a is a potent stimulus for mast cells to release histamine and that it induces histamine release via an active, secretory process.
Who reads Tumor necrosis factor α (TNF-α) activates human adenoidal and cutaneous mast cells to histamine secretion?
It is typically read by researchers, students, and practitioners in Immunology and Microbiology.
- Author
- Ewa Brzezińska-Błaszczyk; Anna Pietrzak
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0165-2478)
- Published
- 1997
- Language
- EN
- Field
- Immunology and Microbiology (Life Sciences)