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Diffuse Bronchiolitis Pattern on a Computed Tomography Scan as a Presentation of Pulmonary Tumor Thrombotic Microangiopathy: a Case Report by Marcos Duarte Guimarães; Maria Fernanda Arruda Almeida; André Brelinger; Paula Nicole Barbosa; Rubens Chojniak; Jefferson Luiz Gross is a Medicine article available to read on EtoBox.
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## Introduction Pulmonary tumor thrombotic microangiopathy is a rare complication of malignant diseases. The diagnosis is extremely difficult and is most often performed after death. Invariably, patients develop acute pulmonary hypertension causing right heart failure, shortness of breath and death in a few days. We describe the clinical and radiological findings of a patient who presented with this complication. ## Case presentation A 28-year-old Caucasian woman with a previous history of pelvic tumor resection two months previously, suggestive of metastatic adenocarcinoma, presented with intense shortness of breath. A computed tomography scan showed signs of acute cor pulmonale and diffuse nodular opacities associated with a tree-in-bud pattern disseminated through her lungs, suggestive of bronchiolitis. Our patient's condition worsened and she underwent a surgical biopsy. Pathologic analysis of the biopsied specimens revealed pulmonary tumor thrombotic microangiopathy. Our patient's tumor evolved from a gastric origin (Krukenberg tumor). She underwent progressive clinical deterioration and died less than 24 hours after the biopsy. None of the cases described previously in the li
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- Author
- Marcos Duarte Guimarães; Maria Fernanda Arruda Almeida; André Brelinger; Paula Nicole Barbosa; Rubens Chojniak; Jefferson Luiz Gross
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); [London]: BioMed Central, 2007-; [London]: 2008-; Springer Science and Business Media LLC (ISSN 1752-1947)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)