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Microneedle-mediated Nanomedicine to Enhance Therapeutic and Diagnostic Efficacy by Yuyang Zuo; Rujie Sun; Nuala Del Piccolo; Molly M. Stevens is a Engineering article available to read on EtoBox.

What is Microneedle-mediated Nanomedicine to Enhance Therapeutic and Diagnostic Efficacy about?

## Abstract Nanomedicine has been extensively explored for therapeutic and diagnostic applications in recent years, owing to its numerous advantages such as controlled release, targeted delivery, and efficient protection of encapsulated agents. Integration of microneedle technologies with nanomedicine has the potential to address current limitations in nanomedicine for drug delivery including relatively low therapeutic efficacy and poor patient compliance and enable theragnostic uses. In this Review, we first summarize representative types of nanomedicine and describe their broad applications. We then outline the current challenges faced by nanomedicine, with a focus on issues related to physical barriers, biological barriers, and patient compliance. Next, we provide an overview of microneedle systems, including their definition, manufacturing strategies, drug release mechanisms, and current advantages and challenges. We also discuss the use of microneedle-mediated nanomedicine systems for therapeutic and diagnostic applications. Finally, we provide a perspective on the current status and future prospects for microneedle-mediated nanomedicine for biomedical applications.

Who reads Microneedle-mediated Nanomedicine to Enhance Therapeutic and Diagnostic Efficacy?

Author

Yuyang Zuo; Rujie Sun; Nuala Del Piccolo; Molly M. Stevens

Publisher

Springer

Published

2024

Language

EN

Field

Engineering (Physical Sciences)