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The CRISPR Growth Spurt: from Bench to Clinic on Versatile Small RNAs by Hadi Bayat; Meysam Omidi; Masoumeh Rajabibazl; Suriana Sabri; Azam Rahimpour is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is The CRISPR Growth Spurt: from Bench to Clinic on Versatile Small RNAs about?

Clustered regulatory interspaced short palindromic repeats (CRISPR) in association with CRISPR-associated protein (Cas) is an adaptive immune system, playing a pivotal role in the defense of bacteria and archaea. Ease of handling and cost effectiveness make the CRISPR-Cas system an ideal programmable nuclease tool. Recent advances in understanding the CRISPR-Cas system have tremendously improved its efficiency. For instance, it is possible to recapitulate the chronicle CRISPR-Cas from its infancy and inaugurate a developed version by generating novel variants of Cas proteins, subduing off-target effects, and optimizing of innovative strategies. In summary, the CRISPR-Cas system could be employed in a number of applications, including providing model systems, rectification of detrimental mutations, and antiviral therapies.

Who reads The CRISPR Growth Spurt: from Bench to Clinic on Versatile Small RNAs?

Author

Hadi Bayat; Meysam Omidi; Masoumeh Rajabibazl; Suriana Sabri; Azam Rahimpour

Publisher

Korean Society for Microbiology and Biotechnology

Published

2016

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)