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Impact of Aortic Root Anatomy and Geometry on Paravalvular Leak in Transcatheter Aortic Valve Replacement With Extremely Large Annuli Using the Edwards SAPIEN 3 Valve by Gilbert H.L. Tang; Syed Zaid; Isaac George; Omar K. Khalique; Yigal Abramowitz; Yoshio Maeno; Raj R. Makkar; Hasan Jilaihawi; Norihiko Kamioka; Vinod H. Thourani; Vasilis Babaliaros; John G. Webb; Nay M. Htun; Adrian Attinger-Toller; Hasan Ahmad; Ryan Kaple; Kapil Sharma; Joseph A. Kozina; Tsuyoshi Kaneko; Pinak Shah; Sameer A. Hirji; Nimesh D. Desai; Saif Anwaruddin; Dinesh Jagasia; Howard C. Herrmann; Sukhdeep S. Basra; Molly A. Szerlip; Michael J. Mack; Moses Mathur; Christina W. Tan; Creighton W. Don; Rahul Sharma; Sameer Gafoor; Ming Zhang; Samir R. Kapadia; Stephanie L. Mick; Amar Krishnaswamy; Nicholas Amoroso; Arash Salemi; S. Chiu Wong; Annapoorna S. Kini; Josep Rodés-Cabau; Martin B. Leon; Susheel K. Kodali is a Medicine article available to read on EtoBox.

What is Impact of Aortic Root Anatomy and Geometry on Paravalvular Leak in Transcatheter Aortic Valve Replacement With Extremely Large Annuli Using the Edwards SAPIEN 3 Valve about?

## Objectives: The aim of this study was to determine factors affecting paravalvular leak (pvl) in transcatheter aortic valve replacement (tavr) with the edwards sapien 3 (s3) valve in extremely large annuli. ## Background: The largest recommended annular area for the 29-mm s3 is 683 mm. however, experience with s3 tavr in annuli >683 mm has not been widely reported. ## Methods: From december 2013 to july 2017, 74 patients across 16 centers with mean area 721 ± 38 mm (range: 684 to 852 mm) underwent s3 tavr. the transfemoral approach was used in 95%, and 39% were under conscious sedation. patient, anatomic, and procedural characteristics were retrospectively analyzed. valve academic research consortium-2 outcomes were reported. ## Results: Procedural success was 100%, with 2 deaths, 1 stroke, and 2 major vascular complications at 30 days. post-dilatation occurred in 32%, with final balloon overfilling (1 to 5 ml extra) in 70% of patients. implantation depth averaged 22.3 ± 12.4% at the noncoronary cusp and 20.7 ± 9.9% at the left coronary cusp. new left bundle branch block occurred in 17%, and 6.3% required new permanent pacemakers. thirty-day echocardiography showed mild pvl in 22

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Author

Gilbert H.L. Tang; Syed Zaid; Isaac George; Omar K. Khalique; Yigal Abramowitz; Yoshio Maeno; Raj R. Makkar; Hasan Jilaihawi; Norihiko Kamioka; Vinod H. Thourani; Vasilis Babaliaros; John G. Webb; Nay M. Htun; Adrian Attinger-Toller; Hasan Ahmad; Ryan Kaple; Kapil Sharma; Joseph A. Kozina; Tsuyoshi Kaneko; Pinak Shah; Sameer A. Hirji; Nimesh D. Desai; Saif Anwaruddin; Dinesh Jagasia; Howard C. Herrmann; Sukhdeep S. Basra; Molly A. Szerlip; Michael J. Mack; Moses Mathur; Christina W. Tan; Creighton W. Don; Rahul Sharma; Sameer Gafoor; Ming Zhang; Samir R. Kapadia; Stephanie L. Mick; Amar Krishnaswamy; Nicholas Amoroso; Arash Salemi; S. Chiu Wong; Annapoorna S. Kini; Josep Rodés-Cabau; Martin B. Leon; Susheel K. Kodali

Publisher

American College of Cardiology; Elsevier ; Elsevier BV (ISSN 1936-8798)

Published

2018

Language

EN

Field

Medicine (Health Sciences)