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S Carboplatin ## Gross haematuria and hydroureteronephrosis: case report A 6-year-old girl developed gross haematuria and hydroureteronephrosis during treatment with carboplatin for low-grade glioma. The girl, who had type 1 neurofibromatosis and seizures, was diagnosed with low-grade glioma after experiencing the left leg weakness. Therefore, she was scheduled to receive chemotherapy with high-dose carboplatin 560 mg/m 2 every 28 days for 13 cycles [route not stated]. After chemotherapy cycle 8, she developed severe vomiting and nausea. Therefore, she was admitted locally for dehydration. Urinalysis showed microscopic haematuria at that time. After chemotherapy cycle 9, she again developed severe vomiting, nausea and gross haematuria with clots. The girl was again admitted and received treatment with IV hydration. Renal ultrasound revealed newly developed bilateral hydroureteronephrosis. Based on these findings and clinical presentation a diagnosis of goss haematuria and hydroureteronephrosis secondary to the carboplatin therapy was made. After 4 days of aggressive hydration treatment, haematuria spontaneously cleared [not all outcomes stated].

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Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Medicine (Health Sciences)