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This study investigates the inhibitory effects of gallic acid on melanogenesis in B16F10 cells, revealing that it significantly reduces melanin synthesis and tyrosinase activity in a dose- and time-dependent manner. Gallic acid operates through the activation of signaling pathways such as PI3K/Akt and MEK/ERK, while down-regulating melanogenesis-related proteins including MITF and tyrosinase. The findings suggest that gallic acid may serve as a potential treatment for skin conditions related to abnormal mel

Author

holybyuns

Language

EN