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Can I read Decreased Bone Density in Severely Handicapped Children and Adults, with Reference to the Influence of Limited Mobility and Anticonvulsant Medication on EtoBox?
Decreased Bone Density in Severely Handicapped Children and Adults, with Reference to the Influence of Limited Mobility and Anticonvulsant Medication by S. Nishiyama; T. Kuwahara; I. Matsuda is a Medicine article available to read on EtoBox.
What is Decreased Bone Density in Severely Handicapped Children and Adults, with Reference to the Influence of Limited Mobility and Anticonvulsant Medication about?
Bone density and related biochemical parameters were investigated in institutionalised children and adults with severe handicaps, who were classified according to the degree of limited mobility (group 1, bed-ridden; group 2, capable of crawling; group 3, capable of walking) and according to whether or not they were receiving anticonvulsants. As determined by microdensitometric analysis of radiograms of the second metacarpal bone, bone width (D), bone pattern area (ZGS) and bone salt density (EGS/D) were decreased in the patients, the decreases being most prominent in group 1, followed by groups 2 and 3, in that order. Significant decreases of ZGS and ZGS/D, but not of D, were found in patients on anticonvulsant treatment in comparison to patients without therapy. Serum alkaline phosphatase (Al-p) and parathyroid hormone (iPTH) as well as urinary calcium and cyclic adenosine-3',5'-monophosphate (cAMP) excretion were significantly increased in group 1. In comparison to patients without therapy, anticonvulsant-treated children showed significantly decreased levels of serum calcium (Ca), ionised Ca (Ca2+), 25-hydroxy vitamin D3 and urinary phosphate (PO4) excretion, and elevated levels
Who reads Decreased Bone Density in Severely Handicapped Children and Adults, with Reference to the Influence of Limited Mobility and Anticonvulsant Medication?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- S. Nishiyama; T. Kuwahara; I. Matsuda
- Publisher
- Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-6997)
- Published
- 1986
- Language
- EN
- Field
- Medicine (Health Sciences)