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What is Insulin Resistance in Diabetic Dyslipidemia about?
Insulin resistance is a key driver of diabetic dyslipidemia, characterized by high triglycerides and low HDL cholesterol levels. Insulin resistance leads to increased free fatty acid flux from adipose tissue to the liver, which contributes to hepatic overproduction of triglyceride-rich very low-density lipoproteins. Insulin resistance also decreases lipoprotein lipase activity, impairing triglyceride clearance and contributing further to elevated triglyceride levels.
- Author
- Raga Manduaru
- Language
- EN