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Risks and Benefits of Concurrent Treatment with Antiplatelet and Anticoagulation Therapy in Post‐op Bioprosthetic Aortic Valve Replacement Patients by Carma Yaghi; Rajeev Masson; Kyoko Yamada; Shiyun Zhu; Christine Fong; Aida Shirazi; Paul LaPunzina; Kenny Mok is a Medicine article available to read on EtoBox.
What is Risks and Benefits of Concurrent Treatment with Antiplatelet and Anticoagulation Therapy in Post‐op Bioprosthetic Aortic Valve Replacement Patients about?
## Background and aim: Among patients receiving surgical bioprosthetic aortic valve replacement (bavr), there is an elevated risk of thromboembolic events postoperatively. however, the risks and benefits of varying anticoagulation strategies remain controversial. the aim of this study is to compare the risks and benefits of aspirin monotherapy to aspirin plus warfarin ("concurrent therapy") in patients receiving bavr. ## Methods: A retrospective cohort study was conducted using patients' data from kaiser permanente northern california, including those who underwent bavr with or without coronary artery bypass grafting between 2009 and 2018. patients were identified as having been discharged with aspirin only or concurrent therapy. the outcomes were mortality, thromboembolic events, and clinically relevant bleeding during a 6-month follow-up. the event rates were compared using the kaplan-meier method. multivariable survival analysis, incorporating propensity scores, was used to estimate adjusted hazard ratios (ahrs) for each outcome. ## Results: The cohort consisted of 3047 patients. approximately 58% of patients received aspirin only and 42% received concurrent therapy. patients wh
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- Author
- Carma Yaghi; Rajeev Masson; Kyoko Yamada; Shiyun Zhu; Christine Fong; Aida Shirazi; Paul LaPunzina; Kenny Mok
- Publisher
- Hindawi Limited
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)