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Diffuse Liver Disease by David Bowden; Cäcilia S. Reiner is a book available to read on EtoBox.
What is Diffuse Liver Disease about?
Non-alcoholic fatty liver disease (NAFLD) represents a global epidemic which is now estimated to affect up to 25% of the world's adult population. Approximately 1 in 5 patients with NAFLD will develop non-alcoholic steatohepatitis (NASH), soon expected to overtake viral hepatitis as the leading cause of cirrhosis worldwide . Noninvasive assessment of NAFLD is therefore of increasing importance given the limitations and risks associated with liver biopsy, in order to enable the diagnosis and monitoring of affected individuals. Although unenhanced computed tomography (CT) may allow the identification of individuals with moderate to severe steatosis, a threshold of 48 Hounsfield Units (HU) being highly specific for its detection, given the associated radiation burden it is an impractical modality for large-scale monitoring and may be confounded by the co-existence of other materials such as iron [2] (Fig. .1). However, advances in magnetic resonance imaging (MRI) have enabled a more comprehensive assessment of steatosis. The most widely utilized technique is that of dual gradient-echo imaging, in which images are acquired with fat and water proton signals being either "inphase" or "ou
- Author
- David Bowden; Cäcilia S. Reiner
- Publisher
- Springer International Publishing AG; Springer
- Published
- 2023
- Language
- EN
- ISBN
- 9783031273551
- Subjects
- Medical, Medicine
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