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Endoscopic bile duct brushing of malignant pancreatic biliary strictures: Retrospective study with comparison of conventional smear and ThinPrep® techniques by Lourdes R. Ylagan; Lucy H. Liu; Horacio M. Maluf is a Medicine article available to read on EtoBox.

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## Abstract Endoscopic bile duct brushing (EBDB) is carried out to differentiate benign from malignant biliary strictures in patients who have pancreaticobiliary disease. The sensitivity of this method for the diagnosis of malignancy is relatively low. The aim of this study is to analyze the cytomorphologic features that are helpful in increasing the sensitivity of detecting these lesions on cytologic samples. These features are compared with slides prepared with the ThinPrep® technique. The study included 142 patients with bile duct obstruction or pancreatic mass who underwent EBDB and follow‐up surgery or biopsy between 1997 to 2000. Twenty‐five (18%) of these cases were positive for malignancy in both EBDB and follow‐up surgical biopsy; 20 of these cases were used as positive controls (PC). Sixty‐one (43%) were negative in both EBDB and follow‐up surgical biopsy specimens, and 21 of those cases were used as negative controls (NC). Fifty‐six (39%) cases were negative/atypical in EBDB cytology but were suspicious or positive in the surgical or biopsy specimens (false‐negative). We identified the cytologic criteria that were helpful in differentiating our positive and negative cont

Who reads Endoscopic bile duct brushing of malignant pancreatic biliary strictures: Retrospective study with comparison of conventional smear and ThinPrep® techniques?

Author

Lourdes R. Ylagan; Lucy H. Liu; Horacio M. Maluf

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 8755-1039)

Published

2003

Language

EN

Field

Medicine (Health Sciences)