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Identification of Human Ventricular Tachycardia Demarcated by Fixed Lines of Conduction Block in a 3-Dimensional Hyperboloid Circuit by Takuro Nishimura; Nathan Shatz; J. Peter Weiss; Michael Zawaneh; Rong Bai; Andrew D. Beaser; Gaurav A. Upadhyay; Zaid A. Aziz; Hemal M. Nayak; Dalise Y. Shatz; Shinsuke Miyazaki; Masahiko Goya; Tetsuo Sasano; Wilber Su; Michael Raiman; Roderick Tung is a Medicine article available to read on EtoBox.

What is Identification of Human Ventricular Tachycardia Demarcated by Fixed Lines of Conduction Block in a 3-Dimensional Hyperboloid Circuit about?

## BACKGROUND: The circuit boundaries for reentrant ventricular tachycardia (VT) have been historically conceptualized within a 2-dimensional (2D) construct, with their fixed or functional nature unresolved. This study aimed to examine the correlation between localized lines of conduction block (LOB) evident during baseline rhythm with lateral isthmus boundaries that 3-dimensionally constrain the VT isthmus as a hyperboloid structure. ## METHODS: A total of 175 VT activation maps were correlated with isochronal late activation maps during baseline rhythm in 106 patients who underwent catheter ablation for scar-related VT from 3 centers (42% nonischemic cardiomyopathy). An overt LOB was defined by a deceleration zone with split potentials (≥20 ms isoelectric segment) during baseline rhythm. A novel application of pacing within deceleration zone (≥600 ms) was implemented to unmask a concealed LOB not evident during baseline rhythm. LOB identified during baseline rhythm or pacing were correlated with isthmus boundaries during VT. ## RESULTS: Among 202 deceleration zones analyzed during baseline rhythm, an overt LOB was evident in 47%. When differential pacing was performed in 38 decel

Who reads Identification of Human Ventricular Tachycardia Demarcated by Fixed Lines of Conduction Block in a 3-Dimensional Hyperboloid Circuit?

Author

Takuro Nishimura; Nathan Shatz; J. Peter Weiss; Michael Zawaneh; Rong Bai; Andrew D. Beaser; Gaurav A. Upadhyay; Zaid A. Aziz; Hemal M. Nayak; Dalise Y. Shatz; Shinsuke Miyazaki; Masahiko Goya; Tetsuo Sasano; Wilber Su; Michael Raiman; Roderick Tung

Publisher

Ovid Technologies (Wolters Kluwer Health)

Published

2023

Field

Medicine (Health Sciences)