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What is Molecularly Imprinted Polymers for GTI Removal about?

This study focuses on the design and synthesis of novel molecularly imprinted polymers (MIPs) for the selective removal of the potentially genotoxic impurity 1,3-diisopropylurea (IPU) from active pharmaceutical ingredient (API) solutions. The MIPs were tested against various APIs, demonstrating a binding capacity of 80% for IPU with minimal non-specific binding to the APIs. The findings indicate that incorporating a carboxylate anion in the MIP enhances its performance in selectively binding the target impu

Author

INTAN FITRIANA SARI

Language

EN