Opening book details…
Can I read Antineutrophil Cytoplasmic Antibodies in Infective Endocarditis: a Case Report and Systematic Review of the Literature on EtoBox?
Antineutrophil Cytoplasmic Antibodies in Infective Endocarditis: a Case Report and Systematic Review of the Literature by Inge C. Van Gool; Jesper Kers; Jaap A. Bakker; Joris I. Rotmans; Y. K. Onno Teng; Martijn P. Bauer is a Medicine article available to read on EtoBox.
What is Antineutrophil Cytoplasmic Antibodies in Infective Endocarditis: a Case Report and Systematic Review of the Literature about?
## Abstract Infective endocarditis (IE) may be misdiagnosed as ANCA-associated vasculitis (AAV), especially when antineutrophil cytoplasmic antibodies (ANCA) are detected. Distinguishing IE from AAV is crucial to guide therapy. However, little is known about ANCA positivity in IE patients. We present a case report and systematic review of the literature on patients with ANCA-positive IE, aiming to provide a comprehensive overview of this entity and to aid clinicians in their decisions when encountering a similar case. A systematic review of papers on original cases of ANCA-positive IE without a previous diagnosis of AAV was conducted on PubMed in accordance with PRISMA-IPD guidelines. A predefined set of clinical, laboratory, and kidney biopsy findings was extracted for each patient and presented as a narrative and quantitative synthesis. A total of 74 reports describing 181 patients with ANCA-positive IE were included (a total of 182 cases including our own case). ANCA positivity was found in 18–43% of patients with IE. Patients usually presented with subacute IE (73%) and had positive cytoplasmic ANCA-staining or anti-proteinase-3 antibodies (79%). Kidney function was impaired in
Who reads Antineutrophil Cytoplasmic Antibodies in Infective Endocarditis: a Case Report and Systematic Review of the Literature?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Inge C. Van Gool; Jesper Kers; Jaap A. Bakker; Joris I. Rotmans; Y. K. Onno Teng; Martijn P. Bauer
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)