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Can I read Cholesteryl-6- O -acyl-α-d-glucopyranoside of Helicobacter pylori relate to relative lysophospholipid content on EtoBox?
Cholesteryl-6- O -acyl-α-d-glucopyranoside of Helicobacter pylori relate to relative lysophospholipid content by Tone Tannæs; Geir Bukholm is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.
What is Cholesteryl-6- O -acyl-α-d-glucopyranoside of Helicobacter pylori relate to relative lysophospholipid content about?
The presence of cholesteryl glucosides and high levels of lysophospholipids are elements making the cell wall of Helicobacter pylori unique. In this study, we have investigated the relationship between lysophospholipid content and cholesteryl glucoside composition of variants of 6 clinical isolates. The samples were characterized by diverse outer membrane phospholipase A activity measured as lysophospholipid content of the cell wall. A pldA negative mutant was also included in the study. Thin-layer chromatography showed that cholesteryl glucosides were present in all samples. However, the distribution of cholesteryl-6-O-acyl-alpha-D-glucopyranoside, cholesteryl-alpha-D-glucopyranoside and cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside varied according to lysophospholipid content. Cholesteryl-6-O-acyl-alpha-D-glucopyranoside was exclusively observed in the isolates/variants with an intact pldA and where a significant amount of lysophospholipids could be demonstrated. High lysophospholipid content destabilizes membranes. The balance between cholesteryl-6-O-acyl-alpha-D-glucopyranoside, cholesteryl-alpha-D-glucopyranoside and cholesteryl-6-O-phosphatidyl-alpha-D-glucopyranoside
Who reads Cholesteryl-6- O -acyl-α-d-glucopyranoside of Helicobacter pylori relate to relative lysophospholipid content?
It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.
- Author
- Tone Tannæs; Geir Bukholm
- Publisher
- John Wiley and Sons; Oxford University Press; Oxford University Press (OUP); Elsevier BV (ISSN 0378-1097)
- Published
- 2005
- Language
- EN
- Field
- Biochemistry, Genetics and Molecular Biology (Life Sciences)