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Development of a Bioactive Dentin Adhesive Resin Modified with Magnesium-doped Synthetic Hydroxyapatite Crystals by Umer Daood; Amr Fawzy is a Engineering article available to read on EtoBox.

What is Development of a Bioactive Dentin Adhesive Resin Modified with Magnesium-doped Synthetic Hydroxyapatite Crystals about?

The aim is to evaluate the development of an experimental multi-mode/Universal resin-based dentin adhesive modified with synthetic Mg2+ doped hydroxyapatite crystals (HAp) having self-remineralization and antibiofilm properties. HAp doped with Mg2+ was prepared by the precipitation method. Experimental adhesives were subjected to degree of conversion and X-ray diffraction test for size and crystal structure. Bond strength was tested, and electron microscopy (SEM/TEM) imaging of resin-dentin interface was done along with nanoleakage, nanoindentation, confocal and Raman analyses. S. mutans was analysed using CLSM images against modified adhesive specimens. Nucleating abilities within the resin-dentin specimens are determined by measuring Ca2+. Alkaline phosphatase, Runx2, and Ocn transcripts are amplified using quantitative polymerase chain reaction (q-PCR). A calcium assay is performed to quantify level of mineralisation. When compared to control adhesives, the 0.5% Hap/Mg2+ containing experimental dentin adhesive demonstrated improved interaction with dentin. The preservation of uniform intact hybrid layer with the absence of nanoleakage indicated dentin bond integrity with 0.5% HA

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Author

Umer Daood; Amr Fawzy

Publisher

Elsevier BV

Published

2023

Language

EN

Field

Engineering (Physical Sciences)