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The stability and distribution of Tc-HIDA in vivo and in vitro by Maureen A. Zivanovic; David M. Taylor; V. Ralph McCready; Simon T. Meller is a Medicine article available to read on EtoBox.

What is The stability and distribution of Tc-HIDA in vivo and in vitro about?

Tc-HIDA is a promising new agent for imaging the biliary system. In this study radiochromatography on paper or Sephadex G25 gel has been used to measure the proportions of TcHIDA, 'hydrolysed Tc' and pertechnetate in solutions from a commercial kit (CIS TCK 15) and in body fluids from patients and rats receiving this radiopharmaceutical. The tissue distribution in male and female rats has shown the radiopharmaceutical to be rapidly removed from the blood by the liver and then excreted via the intestines. There appears to be a sex difference in the uptake in the kidneys and in the urinary excretion in both rats and patients.

Who reads The stability and distribution of Tc-HIDA in vivo and in vitro?

Author

Maureen A. Zivanovic; David M. Taylor; V. Ralph McCready; Simon T. Meller

Publisher

Springer; Springer-Verlag; Springer Verlag; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-6997)

Published

1979

Language

EN

Field

Medicine (Health Sciences)