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This review focuses on the Na/H exchanger NHE3, which plays a critical role in NaCl absorption in the intestine and renal proximal tubule, and is regulated by various extracellular and intracellular signals. The C-terminal domain of NHE3 is essential for its regulation and interaction with cytoskeletal proteins, influencing its trafficking and activity. The document also discusses the physiological implications of NHE3 in nutrient absorption and its involvement in digestive and renal functions, particularly

Author

phamthienhan061106

Language

EN