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This clinical trial evaluated the effectiveness of initiating tenofovir disoproxil fumarate (TDF) at gestational week 16 compared to the standard care of starting TDF at week 28 in preventing mother-to-child transmission (MTCT) of hepatitis B virus (HBV) in pregnant women with high viremia. The results showed that TDF starting at week 16 was noninferior to the standard care, with MTCT rates of 0.76% in the experimental group versus 0% in the control group. The findings support the use of TDF at an earlier g

Author

Gonzalo Ramon De La Cruz

Language

EN