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Balance Measures for Propensity Score Methods: a Clinical Example on Beta-agonist Use and the Risk of Myocardial Infarction by Rolf H. H. Groenwold; Frank de Vries; Anthonius de Boer; Wiebe R. Pestman; Frans H. Rutten; Arno W. Hoes; Olaf H. Klungel is a Medicine article available to read on EtoBox.
What is Balance Measures for Propensity Score Methods: a Clinical Example on Beta-agonist Use and the Risk of Myocardial Infarction about?
## ABSTRACT ## Purpose Propensity score (PS) methods aim to control for confounding by balancing confounders between exposed and unexposed subjects with the same PS. PS balance measures have been compared in simulated data but limited in empirical data. Our objective was to compare balance measures in clinical data and assessed the association between long‐acting inhalation beta‐agonist (LABA) use and myocardial infarction. ## Methods We estimated the relationship between LABA use and myocardial infarction in a cohort of adults with a diagnosis of asthma or chronic obstructive pulmonary disorder from the Utrecht General Practitioner Research Network database. More than two thousand PS models, including information on the observed confounders age, sex, diabetes, cardiovascular disease and chronic obstructive pulmonary disorder status, were applied. The balance of these confounders was assessed using the standardised difference (SD), Kolmogorov–Smirnov (KS) distance and overlapping coefficient. Correlations between these balance measures were calculated. In addition, simulation studies were performed to assess the correlation between balance measures and bias. ## Results LABA use was
Who reads Balance Measures for Propensity Score Methods: a Clinical Example on Beta-agonist Use and the Risk of Myocardial Infarction?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Rolf H. H. Groenwold; Frank de Vries; Anthonius de Boer; Wiebe R. Pestman; Frans H. Rutten; Arno W. Hoes; Olaf H. Klungel
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1053-8569)
- Published
- 2011
- Language
- EN
- Field
- Medicine (Health Sciences)