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Can I read 3D printing with star-shaped strands: A new approach to enhance in vivo bone regeneration on EtoBox?
3D printing with star-shaped strands: A new approach to enhance in vivo bone regeneration by Raymond, Yago (author);Lehmann, Cyril (author);Thorel, Emilie (author);Benitez, Raúl (author);Riveiro, Antonio (author);Pou, Juan (author);Manzanares, Maria-Cristina (author);Franch, Jordi (author);Canal, Cristina (author);Ginebra, Maria-Pau (author) is a Engineering article available to read on EtoBox.
What is 3D printing with star-shaped strands: A new approach to enhance in vivo bone regeneration about?
Concave surfaces have shown to promote bone regeneration in vivo. However, bone scaffolds obtained by direct ink writing, one of the most promising approaches for the fabrication of personalized bone grafts, consist mostly of convex surfaces, since they are obtained by microextrusion of cylindrical strands. By modifying the geometry of the nozzle, it is possible to print 3D structures composed of non-cylindrical strands and favor the presence of concave surfaces. In this work, we compare the in vivo performance of 3D-printed calcium phosphate scaffolds with either conventional cylindrical strands or star-shaped strands, in a rabbit femoral condyle model. Monocortical defects, drilled in contralateral positions, are randomly grafted with the two scaffold configurations, with identical composition. The samples are explanted eight weeks post-surgery and assessed by μ-CT and resin-embedded histological observations. The results reveal that the scaffolds containing star-shaped strands have better osteoconductive properties, guiding the newly formed bone faster towards the core of the scaffolds, and enhance bone regeneration, although the increase is not statistically significant (p > 0.
Who reads 3D printing with star-shaped strands: A new approach to enhance in vivo bone regeneration?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- Raymond, Yago (author);Lehmann, Cyril (author);Thorel, Emilie (author);Benitez, Raúl (author);Riveiro, Antonio (author);Pou, Juan (author);Manzanares, Maria-Cristina (author);Franch, Jordi (author);Canal, Cristina (author);Ginebra, Maria-Pau (author)
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Engineering (Physical Sciences)