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A Clinicopathologic Study of Mucinous Gastric Carcinoma Including Multivariate Analysis by Chun-Ying Wu; Hong-Zen Yeh; Rocky Tai-Ping Shih; Gran-Hum Chen is a Medicine article available to read on EtoBox.

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## BACKGROUND. Mucinous gastric carcinoma (MGC) is a rare subtype of gastric adenocarcinoma, and its clinical and pathologic features are still controversial. To clarify the significance of this subtype of carcinoma, the authors conducted a case-control study to investigate the clinicopathologic characteristics of MGC and determine whether this mucin-producing histologic type is associated with a worse prognosis than other gastric carcinomas. ## METHODS. Twenty-two cases of MGC and 46 patients with nonmucinous gastric carcinoma (NGC) were included. Patients were evaluated on the basis of age, gender, tumor size, location, depth of tumor invasion, histologic differentiation, lymph node involvement, organ metastasis, stage at presentation, surgical curability, adjuvant chemotherapy and radiation therapy. To determine whether the MGC itself was an independent prognostic factor, a multivariate analysis was performed with the Cox proportional hazards model. ## RESULTS. The MGC patients were found to have larger tumors (P Ͻ 0.001), tumors more often located in the upper stomach (P Ͻ 0.05), more serosal invasion (P Ͻ 0.05), more lymph node involvement (P Ͻ 0.05), greater frequency of adva

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Author

Chun-Ying Wu; Hong-Zen Yeh; Rocky Tai-Ping Shih; Gran-Hum Chen

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0008-543X)

Published

1998

Language

EN

Field

Medicine (Health Sciences)