Can I read Farnesol: An approach on biofilms and nanotechnology on EtoBox?

Farnesol: An approach on biofilms and nanotechnology by Adelaide Fernandes Costa; Lívia do Carmo Silva; Andre Correa Amaral is a Medicine article available to read on EtoBox.

What is Farnesol: An approach on biofilms and nanotechnology about?

## Abstract Biofilms are important virulence factor in infections caused by microorganisms because of its complex structure, which provide resistance to conventional antimicrobials. Strategies involving the use of molecules capable of inhibiting their formation and also act synergistically with conventional drugs have been explored. Farnesol is a molecule present in essential oils and produced by Candida albicans as a quorum sensing component. This sesquiterpene presents inhibitory properties in the formation of microbial biofilms and synergism with antimicrobials used in clinical practice, and can be exploited even for eradication of biofilms formed by drug-resistant microorganisms. Despite this, farnesol has physical and chemical characteristics that can limit its use, such as high hydrophobicity and volatility. Therefore, nanotechnology may represent an option to improve the efficiency of this molecule in high complex environments such as biofilms. Nanostructured systems present important results in the improvement of treatment with different commercial drugs and molecules with therapeutic or preventive potential. The formation of nanoparticles offers advantages such as protecti

Who reads Farnesol: An approach on biofilms and nanotechnology?

Author

Adelaide Fernandes Costa; Lívia do Carmo Silva; Andre Correa Amaral

Publisher

Oxford University Press (OUP)

Published

2021

Language

EN

Field

Medicine (Health Sciences)