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Bordetella pertussis Strain Analysis by fznmomin is a document available to read on EtoBox.
This document summarizes the characterization of a Bordetella pertussis strain (designated I979) isolated from an unvaccinated infant in New York in 2013 that lacked two key components of acellular pertussis vaccines - pertussis toxin and pertactin. Whole genome sequencing showed I979 carried the same 28kb deletion in its genome as a pertussis toxin-deficient French strain from 2004. Both strains lacked genes encoding the pertussis toxin virulence factor and the pertactin vaccine antigen due to this deletio
- Author
- fznmomin
- Language
- EN