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CoMet—a web server for comparative functional profiling of metagenomes by Thomas Lingner; Kathrin Petra Aßhauer; Fabian Schreiber; Peter Meinicke is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is CoMet—a web server for comparative functional profiling of metagenomes about?

Analyzing the functional potential of newly sequenced genomes and metagenomes has become a common task in biomedical and biological research. With the advent of high-throughput sequencing technologies comparative metagenomics opens the way to elucidate the genetically determined similarities and differences of complex microbial communities. We developed the web server ‘CoMet’ (http://comet.gobics.de), which provides an easy-to-use comparative metagenomics platform that is well-suitable for the analysis of large collections of metagenomic short read data. CoMet combines the ORF finding and subsequent assignment of protein sequences to Pfam domain families with a comparative statistical analysis. Besides comprehensive tabular data files, the CoMet server also provides visually interpretable output in terms of hierarchical clustering and multi-dimensional scaling plots and thus allows a quick overview of a given set of metagenomic samples.

Who reads CoMet—a web server for comparative functional profiling of metagenomes?

Author

Thomas Lingner; Kathrin Petra Aßhauer; Fabian Schreiber; Peter Meinicke

Publisher

Oxford University Press; London: Information Retrieval; Oxford: Oxford University Press; Oxford University Press (OUP) (ISSN 0305-1048)

Published

2011

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)